Central Retinal Vein Occlusion: Current Therapeutic Approach

Central Retinal Vein Occlusion (CRVO) is a common disease causing loss of vision and even blindness. Although CRVO is among the most common vascular disorders affecting the retina, second in prevalence only to diabetic retinopathy, and it has been known for more than 150 years, there is a great deal of confusion regarding its management. The pathogenesis of CRVO is multifactorial with both local factors and systemic diseases being etiologically important. There are still gaps in understanding the etiology and pathogenesis of this circulatory disorder. Various new therapeutic approaches have been developed in the past few years.The objective of this review is to evaluate the treatments commonly advocated, emphasizing evidence-based ones, in the light of our current scientific knowledge of CRVO.